Search results for "Pyrazinoic acid"

showing 2 items of 2 documents

Spectrum of pncA Mutations in Multidrug-Resistant Mycobacterium tuberculosis Isolates Obtained in Latvia

2004

Pyrazinamide (PZA) is an effective antituberculous agent ([1][1]) that becomes active when bacterial pyrazinamidase converts it to pyrazinoic acid, which is toxic to mycobacteria ([4][2]). In Mycobacerium tuberculosis , PZA resistance is associated with the loss of pyrazinamidase activity, mainly

TuberculosisAntitubercular AgentsAmidohydrolasesMicrobiologyMycobacterium tuberculosischemistry.chemical_compoundPyrazinoic acidDrug Resistance Multiple BacterialmedicineHumansTuberculosisPharmacology (medical)Multidrug-Resistant Mycobacterium tuberculosisCodonLetters to the EditorPharmacologybiologyReverse Transcriptase Polymerase Chain ReactionMycobacterium tuberculosisPyrazinamidebiology.organism_classificationmedicine.diseaseLatviaPyrazinamideVirologyInfectious DiseaseschemistryMutationPncAmedicine.drugAntimicrobial Agents and Chemotherapy
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Crystal structure of a 1:1 salt of 4-amino­benzoic acid (vitamin B10) with pyrazinoic acid

2018

The paper reports the crystal structure of novel salt of 4-amino­benzoic acid (Vitamin B10) with pyrazinoic acid.

inorganic chemicalscrystal structure4-amino­benzoic acidmelting pointStackingchemical and pharmacologic phenomena02 engineering and technologyCrystal structure010402 general chemistry01 natural sciencesCocrystalResearch Communicationslcsh:ChemistryCrystalchemistry.chemical_compoundPyrazinoic acidpyrazinoic acid4-Aminobenzoic acidsaltGeneral Materials ScienceBenzoic acidHydrogen bondChemistryorganic chemicalshemic and immune systemsGeneral Chemistry021001 nanoscience & nanotechnologyCondensed Matter Physicshydrogen bonding0104 chemical sciencesCrystallography4-aminobenzoic acidlcsh:QD1-9990210 nano-technologyActa Crystallographica Section E: Crystallographic Communications
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